The Whodunit Card Game: "Murder in the big city, and you must solve the crime. Brenda's dead, and foul play is suspected. To win, find out who did it, where, when, how, and why."
This is a card game that shares some similarities with Clue, but adds some other questions to the mix, like what time of day did it happen, and what was the killer's motive? To the usual process of elimination and deduction found in most Clue-type games, they've added scoring elements. You can collect sets of clues and reveal them to score points. Obviously, though, this aids the other players as well by eliminating some categories.
You start with a number of cards, each of which contains a specific clue. As play progresses, you can attempt to accumulate all the clues in a category, which will earn you points based on what turn you choose to reveal your set.